
자가추출활성세포가 노화되면, 세포 형태는
길고 가는 방추형에서 크고 납작한 형태로 변하고
성장인자, 세포 부착 인자, 항염증 인자 등의
분비 능력이 감소하여 면역조절 능력도 떨어집니다.
It has been proven that with the senescence of hUC-MSCs, the morphology of the cells
changes from elongated fusiform to large and flat (Fig. 4), and the ability of secreting
factors also decreases with senescence, such as growth factors, cell adhesion and
anti-inflammatory factors, manifested as decreased immunomodulatory capacity.